Research Volunteers Needed

What is the link between
migraine and depression?
The World Health Organisation (WHO) have recently published data suggesting that depression is one of the leading causes of years of life lived with disability. Migraine is rated as 18th on the same list. Several studies have identified that many migraine sufferers also have symptoms of depression (even if only mild), but the reasons for this link remain unclear.
Staff at the City of London Migraine Clinic are looking for volunteers with migraine and depression to take part in a new 4-month study to assess the effects of treating both conditions at the same time. Even if you do not think you are depressed, you may still be eligible for the studysometimes depression is not always obvious but it can be assessed quite easily using a simple questionnaire.

If you would like further information about this study please send a stamped self-addressed envelope to:
Mrs Alison Frith, Clinical Research Sister, The City of London Migraine Clinic, 22 Charterhouse Square, London EC1M 6DX.
Alternatively ring Alison on 020 7251 8094
for an informal chat.

Clinical Research Study
Episodic Cluster Headache
If you suffer from Episodic Cluster Headache you may qualify to participate in a clinical research study of an investigational intranasal medication being conducted.

You must
• Be 18 years or older
• Have had Episodic Cluster Headache for at least 2 years
• Have had at least 2 previous ciuster headache episodes
• Expect your usual cluster episode to last at least 6 weeks but not more than 16 weeks.

Study Design:
If qualified, you will enrol into a Screening Period when you are not having headaches.
When the headache cycle begins you will complete headache diaries each day of the study.
A 7-day Treatment Period with nasal spray of either study drug or placebo (an inactive substance).
You have twice the chance of receiving active drug than receiving placebo.
Following treatment there will be a 6-week Follow-Up Period

If you are interested, please contact
Alison Frith Clinical Research Sister The City of London Migraine Clinic 22 Charterhouse Square London EC1M 6DX
Tel (020) 7251 8094 Fax (020) 74902183